Efficacy and safety of HSK21542 for pruritus management in hemodialysis patients: a multicenter, randomized, double-blind, placebo-controlled trial

The 0.3 μg/kg dose of HSK21542 demonstrated superior efficacy and safety in reducing pruritus and improving quality of life in hemodialysis patients.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2025-06-24
DOI
https://doi.org/10.3389/fphar.2025.1583515
Citations
4
Primary Topic
Dermatology and Skin Diseases
Type
article
Field-Weighted Citation Impact
8.02
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Efficacy and safety of HSK21542 for pruritus management in hemodialysis patients: a multicenter, randomized, double-blind, placebo-controlled trial

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Frontiers in Pharmacology
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article

Efficacy and safety of HSK21542 for pruritus management in hemodialysis patients: a multicenter, randomized, double-blind, placebo-controlled trial

Changlin Mei, Li Zhou, Min Gao, Tianjun Guan, Dong Sun, Chao-Qing Wu, Bi‐Cheng Liu, Qinkai Chen, Yan Xu, Rui Yan, Zhanzheng Zhao, Li Yao, Yaming Li, Hui Xu, Ming Shi, Mingming Pan, Wan‐yun Zhao
article en
4 citations

Abstract

The 0.3 μg/kg dose of HSK21542 demonstrated superior efficacy and safety in reducing pruritus and improving quality of life in hemodialysis patients.

Frontiers in PharmacologyVol. 16
Qingdao University (CN), Central South University (CN), Nanchang University (CN), Guiyang Medical University (CN), Xuzhou Medical College (CN), Second Military Medical University (CN), Sichuan University (CN), Wuhan University (CN), West China Hospital of Sichuan University (CN), China National Pharmaceutical Group Corporation (China) (CN), Zhongda Hospital Southeast University (CN), Affiliated Hospital of Guizhou Medical University (CN), The People's Hospital of Guangxi Zhuang Autonomous Region (CN), Affiliated Hospital of Qingdao University (CN), Zhongshan Hospital of Xiamen University (CN), Renmin Hospital of Wuhan University (CN), First Hospital of China Medical University (CN), First Affiliated Hospital of Zhengzhou University (CN), Xiangya Hospital Central South University (CN), Shanghai Zhabei District Shibei Hospital (CN), First Affiliated Hospital of Nanchang University (CN), China Medical University (CN)
Responsible consumption and production
Openalex Percentile: Top 3%
Dermatology and Skin Diseases
8.02
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