CORRELATION OF RENAL RESISTIVE INDEX WITH SERUM CREATININE AND ALBUMINURIA IN PATIENTS OF DIABETIC NEPHROPATHY

One metabolic disease known as diabetes mellitus is typified by symptoms resulting from either incorrect insulin action, problems in internal secretion, or both. The frequency of type 2 diabetes is rising in Pakistan, and co-morbid conditions including obesity, a family history of the disease, and hypertension appear to enhance the chance of developing the condition. One severe microvascular consequence of diabetes mellitus is diabetic nephropathy. According to estimates, diabetics are significantly more likely than non-diabetics to die from renal failure. Objective: To determine correlation of renal resistive index with serum creatinine and albuminuria in patients of diabetic nephropathy. Methodology Setting: Department of diagnostic radiology, Combined Military Hospital Malir Study design: Cross-sectional study Duration: 6-months after approval of synopsis. Sample size: 190 patients was calculated through STATA 15 using formula for one sample correlation. The study was conducted after permission from ethical review committee. A total of 190 patients referred to diagnostic radiology department for ultrasound KUB/abdomen, fulfilling the inclusion criteria, were enrolled after informed consent. The baseline characteristics including age, gender, duration of diabetes, hypertension and smoking were recorded. A real-time B-scan were used to view the kidneys first, followed by a duplex Doppler ultrasonography to check the intrarenal arteries. Each kidney's upper, middle, and lower intrarenal arteries had at least three measurements made. The machine used a predefined calculation to determine the RI value. Results: There were 85 (44.7%) females and 105 (55.3%) males. Hypertension was reported by 68.9% of respondents. Smoking prevalence was lower, with 37.4%. The average duration of diabetes is 8.6 ± 2.5 years, with a range of 5 to 15 years. A measure of kidney vascular resistance, the renal resistive index (RRI) has a mean of 0.71 ± 0.04 and a narrow range of 0.60 to 0.80. Conclusion: It is concluded, our study supports the use of RRI as a valuable, non-invasive marker that correlates well with serum creatinine and albuminuria in diabetic nephropathy.