Sulopenem versus Amoxicillin/Clavulanate for the Treatment of Uncomplicated Urinary Tract Infection

Sulopenem was noninferior to amoxicillin/clavulanate for the treatment of adult women with uncomplicated urinary tract infection, but was associated with more frequent mild adverse events. (Funded by Iterum Therapeutics; REASSURE ClinicalTrials.gov number, NCT05584657.).

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Publication Details

Journal
NEJM Evidence
Published
2025-06-24
DOI
https://doi.org/10.1056/evidoa2400414
Citations
6
Primary Topic
Urinary Tract Infections Management
Type
article
Field-Weighted Citation Impact
8.13
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article

Sulopenem versus Amoxicillin/Clavulanate for the Treatment of Uncomplicated Urinary Tract Infection

Sailaja Puttagunta, Michael W. Dunne, Steven I. Aronin, Jayanti Gupta et al.
6 citations
NEJM Evidence
Urinary Tract Infections Management
8.13
article

Sulopenem versus Amoxicillin/Clavulanate for the Treatment of Uncomplicated Urinary Tract Infection

Sailaja Puttagunta, Michael W. Dunne, Steven I. Aronin, Jayanti Gupta, Anita Das, Kalpana Gupta
article en
6 citations

Abstract

Sulopenem was noninferior to amoxicillin/clavulanate for the treatment of adult women with uncomplicated urinary tract infection, but was associated with more frequent mild adverse events. (Funded by Iterum Therapeutics; REASSURE ClinicalTrials.gov number, NCT05584657.).

NEJM EvidenceVol. 4(7)
Boston University (US), Fulcrum Therapeutics (United States) (US), West County Health Centers (US)
Zero hunger
Openalex Percentile: Top 2%
Urinary Tract Infections Management
8.13
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