Designing an apoptosis reporter by mutagenesis-based insertion of caspase-3 cleavage motif into green fluorescence protein
Our method does not require additional peptides, which makes it easily adaptable to other systems. And, our apoptosis reporter may be useful in a variety of research fields as well as drug screening.
Authors
- Hakjin Kim
- Sun‐Uk Kim (ORCID: https://orcid.org/0000-0002-5168-6976)
- Kyung‐Sook Chung (ORCID: https://orcid.org/0000-0002-0862-0779)
- Hae-Jun Yang
- Taeho Kwon (ORCID: https://orcid.org/0000-0001-9489-0283)
- Hong Jun Lee
- Young‐Ho Park (ORCID: https://orcid.org/0000-0001-5405-1231)
- Dong‐Seok Lee (ORCID: https://orcid.org/0000-0002-7106-1615)
- In-Sung Song
- Dong Gil Lee
- Unbin Chae
Institutions
- Chungbuk National University (KR)
- Kyungpook National University (KR)
- University of Ulsan (KR)
- Korea Research Institute of Bioscience and Biotechnology (KR)
- Korea University of Science and Technology (KR)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1016/j.jare.2025.06.070
- Citations
- 1
- Primary Topic
- Cell death mechanisms and regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.81