Developing a Scanning Electron Microscopy Approach to Evaluate Paclitaxel Deposition From Drug Coated Balloons in a Human Cadaveric Peripheral Artery Disease Model

This SEM based method effectively evaluated drug transfer in human PAD lesions, revealing greater drug delivery in smooth lesions and the impact of vessel preparation. This novel analytic model offers a platform for optimising DCB strategies to improve PAD patient outcomes.

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Publication Details

Journal
EJVES Vascular Forum
Published
2025-01-01
DOI
https://doi.org/10.1016/j.ejvsvf.2025.06.004
Primary Topic
Cerebrovascular and Carotid Artery Diseases
Type
article
Field-Weighted Citation Impact
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article

Developing a Scanning Electron Microscopy Approach to Evaluate Paclitaxel Deposition From Drug Coated Balloons in a Human Cadaveric Peripheral Artery Disease Model

Bright Benfor, Kenneth A. Boateng, Judit Csőre, Stuart J. Corr et al.
EJVES Vascular Forum
Cerebrovascular and Carotid Artery Diseases
article

Developing a Scanning Electron Microscopy Approach to Evaluate Paclitaxel Deposition From Drug Coated Balloons in a Human Cadaveric Peripheral Artery Disease Model

Bright Benfor, Kenneth A. Boateng, Judit Csőre, Stuart J. Corr, Alexander Crichton, Jianhua Gu, Trisha Roy
article en

Abstract

This SEM based method effectively evaluated drug transfer in human PAD lesions, revealing greater drug delivery in smooth lesions and the impact of vessel preparation. This novel analytic model offers a platform for optimising DCB strategies to improve PAD patient outcomes.

EJVES Vascular ForumVol. 64
Semmelweis University (HU), Houston Methodist (US), Methodist Hospital (US)
Good health and well-being
Openalex Percentile: Top 76%
Cerebrovascular and Carotid Artery Diseases
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