Extensively Drug-Resistant <i>Neisseria gonorrhoeae</i> Strain, Canada

We identified a case of extensively drug-resistant (ceftriaxone- and cefixime-resistant and high-level azithromycin-resistant) Neisseria gonorrhoeae in Canada. The strain harbors the penA 60.001 allele, which includes the A311V and 23S rRNA A2059G single-nucleotide polymorphisms associated with high-level azithromycin resistance. The infection was likely acquired during travel in Cambodia.

Authors

Brigitte Lefebvre
Claude Fortin (ORCID: https://orcid.org/0000-0001-9334-3093)
Judith Fafard (ORCID: https://orcid.org/0000-0003-4355-1294)
Irene Martín (ORCID: https://orcid.org/0000-0002-3941-5583)
Robyn Thorington
Andrew Bui-Nguyen
Julian Gitelman (ORCID: https://orcid.org/0000-0003-0052-5520)

Publication Details

Journal: Emerging infectious diseases
Published: 2025-06-24
DOI: https://doi.org/10.3201/eid3107.250023
Citations: 2
Primary Topic: Reproductive tract infections research
Type: article
Field-Weighted Citation Impact: 2.37

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article

Extensively Drug-Resistant Neisseria gonorrhoeae Strain, Canada

Brigitte Lefebvre, Claude Fortin, Judith Fafard, Irene Martín et al.

Jun 24, 2025

2 citations

Emerging infectious diseases

Reproductive tract infections research

2.37

article

Extensively Drug-Resistant Neisseria gonorrhoeae Strain, Canada

Brigitte Lefebvre, Claude Fortin, Judith Fafard, Irene Martín, Robyn Thorington, Andrew Bui-Nguyen, Julian Gitelman

June 24, 2025article en

2 citations

Abstract

We identified a case of extensively drug-resistant (ceftriaxone- and cefixime-resistant and high-level azithromycin-resistant) Neisseria gonorrhoeae in Canada. The strain harbors the penA 60.001 allele, which includes the A311V and 23S rRNA A2059G single-nucleotide polymorphisms associated with high-level azithromycin resistance. The infection was likely acquired during travel in Cambodia.

Emerging infectious diseasesVol. 31(7)

Openalex Percentile: Top 11%

Reproductive tract infections research

2.37

DOI Open Access PDF OpenAlex

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