Antimicrobial resistance in Africa: A retrospective analysis of data from 14 countries, 2016–2019
Analysis of the largest retrospective AMR dataset in Africa indicates high variability in AMR prevalence across countries, coupled with differences in AMR testing capacities, data quality, and AMR estimates. Gaps in AST practices and inadequate digital infrastructures for data collection and reporting represent barriers to estimating the true AMR burden in the region. These barriers warrant large-scale investments to expand healthcare access and strengthen bacteriology laboratory capacities.
Authors
- Pascale Ondoa (ORCID: https://orcid.org/0000-0002-2700-9000)
- Martin Matu
- Eili Klein (ORCID: https://orcid.org/0000-0002-1304-5289)
- Gilbert Osena (ORCID: https://orcid.org/0000-0003-4998-7224)
- Yewande Alimi (ORCID: https://orcid.org/0000-0002-2984-7817)
- Timothée Ouassa (ORCID: https://orcid.org/0000-0002-5456-3103)
- Sehr Brar (ORCID: https://orcid.org/0000-0003-4979-3200)
- Abdourahmane Sow (ORCID: https://orcid.org/0000-0002-0197-5817)
- Erta Kalanxhi (ORCID: https://orcid.org/0000-0002-3614-6058)
- Edwin Shumba (ORCID: https://orcid.org/0000-0002-9942-8490)
- Ramanan Laxminarayan (ORCID: https://orcid.org/0000-0002-1390-9016)
- Geetanjali Kapoor (ORCID: https://orcid.org/0000-0002-8180-171X)
- Manuel Moreira (ORCID: https://orcid.org/0000-0002-4563-5873)
Institutions
- African Union Commission (ET)
- Johns Hopkins University (US)
- Princeton University (US)
- Africa Centres for Disease Control and Prevention (ET)
- Karnataka Health Promotion Trust (IN)
- Amsterdam Institute for Global Health and Development (NL)
- India Health Action Trust (IN)
- Innovative Research (United States) (US)
- West African Health Organisation (BF)
- African Society for Laboratory Medicine (ET)
- East, Central and Southern Africa Health Community (TZ)
- University of Gothenburg (SE)
Publication Details
- Journal
- PLoS Medicine
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1371/journal.pmed.1004638
- Citations
- 13
- Primary Topic
- Antibiotic Use and Resistance
- Type
- article
- Field-Weighted Citation Impact
- 16.40
Funders
- Department of Health and Social Care
- Centers for Disease Control and Prevention