Magnitude of multidrug-resistant and extended-spectrum β-lactamase-producing gram-negative bacteria from tracheal aspirates of intensive care unit patients in Ethiopia
A high magnitude of MDR and ESBL was detected. In addition, there was high resistance to cephalosporin-class antibiotics, which is concerning. The MDRs Acinetobacter spp. and K. pneumoniae were the predominant isolates. Regular monitoring of antimicrobial resistance levels, implementing antimicrobial stewardship, and an effective infection control program should be strengthened.
Authors
- Zenebe Gebreyohannes Berhe (ORCID: https://orcid.org/0009-0003-0002-1768)
- Gizachew Taddesse Akalu (ORCID: https://orcid.org/0000-0002-2603-145X)
- Elias Alehegn
- Rozina Ambachew Geremew
- Tesfa Addis
- Mahlet Abayneh
- Shambel Araya (ORCID: https://orcid.org/0000-0002-0109-6062)
- Kasahun Gorems (ORCID: https://orcid.org/0000-0003-3192-0582)
- Ashenafi Alemu Wami
- Firehiwot Workneh (ORCID: https://orcid.org/0000-0003-1529-987X)
- Alganesh Gebreyohanns
- Gadissa Bedada Hundie (ORCID: https://orcid.org/0000-0002-5627-9675)
- Semaria Solomon (ORCID: https://orcid.org/0000-0002-7412-9400)
- Daniel Kahase Gebrelibanos
- Tsedale Woldu Hadgu
- Yonas Kahasay
- Fitsum Girma Teshome
- Tibebe Adinew
- Shalom Tsegaye Zergaw
- Natnael Dejene Engida
Institutions
- Addis Continental Institute of Public Health (ET)
- Wolkite University (ET)
- Ethiopian Public Health Institute (ET)
- St. Paul's Hospital Millennium Medical College (ET)
- Armauer Hansen Research Institute (ET)
- Addis Ababa University (ET)
- Monash University (AU)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1371/journal.pone.0324199
- Citations
- 1
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 0.59