Non-invasive tape sampling of tryptophan and kynurenine in relation to phenylalanine and tyrosine from melanoma and adjacent non-lesional skin: A pilot study
Non-invasive skin sampling revealed elevated Tyr, Phe, Trp and Kyn levels in MM skin, which is likely the result of compromised skin barrier at this stage of cutaneous melanoma.
Authors
- Tautgirdas Ruzgas (ORCID: https://orcid.org/0000-0003-0304-7528)
- Peter Spégel
- Martin Malmsten (ORCID: https://orcid.org/0000-0003-0046-5599)
- Skaidre Jankovskaja (ORCID: https://orcid.org/0000-0001-7038-0633)
- Sebastian Björklund (ORCID: https://orcid.org/0000-0001-6254-8539)
- Jeremy Bost (ORCID: https://orcid.org/0000-0002-3804-0521)
- Gustav Christensen (ORCID: https://orcid.org/0000-0001-6797-1301)
- Maxim Morin (ORCID: https://orcid.org/0000-0001-8720-3705)
- Johan Engblom
- Oksana Rogova (ORCID: https://orcid.org/0000-0002-5104-2943)
- Merete Hædersdal (ORCID: https://orcid.org/0000-0003-1250-2035)
- K. Nielsen (ORCID: https://orcid.org/0000-0002-7363-0455)
- Chris Anderson
Institutions
- Linköping University (SE)
- University of Copenhagen (DK)
- Malmö University (SE)
- Lund University (SE)
- Bispebjerg Hospital (DK)
- Copenhagen University Hospital (DK)
- Skåne University Hospital (SE)
- BioSurfaces (United States) (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1371/journal.pone.0326457
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Gyllenstiernska Krapperupsstiftelsen
- Stiftelsen för Kunskaps- och Kompetensutveckling
- Lunds Universitet
- Skånes universitetssjukhus
- HudFonden
- Interreg