Secure Gene Profile with AES Encryption and Blockchain

The rapid growth of genomic science calls for the safe storage and communication of private gene information. The classic approach using centralized databases exposes gene information to the possibility of being leaked or hacked into, prompting a strong demand for better security methods. In this paper, a novel method in applying Advanced Encryption Standard (AES) encryption integrated with blockchain is developed. Before uploading the gene datasets to the Ganache blockchain, the system secures them using file hashes that are generated with SHA-256’s smart contract combination controlled by MataMask. In this way, the environment is more secure and is able to store the encoded gene datasets in a way that is vitiation resistant, secure, and traceable. There is a user interface through which are subsequently authenticated, encrypted by an administrator, and then stored in blockchain. There are advanced analytics and visualization techniques that can be applied to the gene data without violation privacy. The proposed model shows that it is possible to achieve genome data protection by implementing AES encryption in blockchain for effective data management, eliminating the data security gaps associated with precision medicine and personalized healthcare.