An Interesting Presentation of Hypercalcaemia in a Middle-Aged Male

A 41-year-old male presented to the Emergency Department with hypercalcaemia and acute kidney injury. He initially presented with bilateral parotid swelling which was treated as mumps. This was later investigated for suspected Sjögren's syndrome, but further evaluation led to a diagnosis of sarcoidosis. Imaging confirmed extensive mediastinal and hilar lymphadenopathy, and a skin biopsy revealed non-caseating granulomas, confirming sarcoidosis. This case highlights the complexity of diagnosing hypercalcaemia and the importance of considering systemic granulomatous diseases like sarcoidosis in the differential diagnoses.

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Publication Details

Journal
Cureus
Published
2025-06-24
DOI
https://doi.org/10.7759/cureus.86682
Primary Topic
Sarcoidosis and Beryllium Toxicity Research
Type
article
Field-Weighted Citation Impact
0.00
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article

An Interesting Presentation of Hypercalcaemia in a Middle-Aged Male

Rehan Siddique, Ankur Patel, Amber Khan
Cureus
Sarcoidosis and Beryllium Toxicity Research
article

An Interesting Presentation of Hypercalcaemia in a Middle-Aged Male

Rehan Siddique, Ankur Patel, Amber Khan
article en

Abstract

A 41-year-old male presented to the Emergency Department with hypercalcaemia and acute kidney injury. He initially presented with bilateral parotid swelling which was treated as mumps. This was later investigated for suspected Sjögren's syndrome, but further evaluation led to a diagnosis of sarcoidosis. Imaging confirmed extensive mediastinal and hilar lymphadenopathy, and a skin biopsy revealed non-caseating granulomas, confirming sarcoidosis. This case highlights the complexity of diagnosing hypercalcaemia and the importance of considering systemic granulomatous diseases like sarcoidosis in the differential diagnoses.

CureusVol. 17(6)
Salford Royal Hospital (GB)
Gender equality
Openalex Percentile: Top 80%
Sarcoidosis and Beryllium Toxicity Research
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