Safety and Efficacy of High-Dosage Infliximab in Recalcitrant Retinal Vasculitis

In this retrospective study, medium- and high-dosage IFX+ achieved better inflammation control and visual outcomes versus low-dosage IFX+, with no additional safety concerns, in treating recalcitrant non-infectious inflammatory RV. Early initiation at greater dosages may optimize IFX response, reduce treatment duration, and improve health-related quality of life.

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Publication Details

Journal
Ocular Immunology and Inflammation
Published
2025-06-24
DOI
https://doi.org/10.1080/09273948.2025.2504577
Primary Topic
Ocular Diseases and Behçet’s Syndrome
Type
article
Field-Weighted Citation Impact
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article

Safety and Efficacy of High-Dosage Infliximab in Recalcitrant Retinal Vasculitis

Thitiporn Thongborisuth, Yanliang Li, Ann-Marie Lobo-Chan, Nadera Sweiss et al.
Ocular Immunology and Inflammation
Ocular Diseases and Behçet’s Syndrome
article

Safety and Efficacy of High-Dosage Infliximab in Recalcitrant Retinal Vasculitis

Thitiporn Thongborisuth, Yanliang Li, Ann-Marie Lobo-Chan, Nadera Sweiss, Ryan Lee, Pooja Bhat, Nissim Stolberg
article en

Abstract

In this retrospective study, medium- and high-dosage IFX+ achieved better inflammation control and visual outcomes versus low-dosage IFX+, with no additional safety concerns, in treating recalcitrant non-infectious inflammatory RV. Early initiation at greater dosages may optimize IFX response, reduce treatment duration, and improve health-related quality of life.

Ocular Immunology and Inflammation
University of Jordan (JO), Mahidol University (TH), University of Illinois Chicago (US)
Openalex Percentile: Top 77%
Ocular Diseases and Behçet’s Syndrome
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