Pharmacokinetic modelling during long-term anesthesia: minimizing the gap
The augmented model with MPC minimizes drug trapping and reduces total drug use, lowering overdose risk and supporting safer anesthesia management.
Authors
- Clara M. Ionescu (ORCID: https://orcid.org/0000-0001-7685-035X)
- Robin De Keyser
- Hamed Farbakhsh (ORCID: https://orcid.org/0000-0001-5550-8889)
- Martine Neckebroek
- Erhan Yumuk (ORCID: https://orcid.org/0000-0001-9416-6690)
- Isabela Birs (ORCID: https://orcid.org/0000-0001-5658-850X)
- Amani R. Ynineb (ORCID: https://orcid.org/0009-0004-9642-2810)
- Dana Copoţ (ORCID: https://orcid.org/0000-0002-6010-830X)
- Samir Ladaci (ORCID: https://orcid.org/0000-0001-6931-4911)
- Cristina I. Mureşan (ORCID: https://orcid.org/0000-0003-2301-4133)
- Ghada Ben Othman (ORCID: https://orcid.org/0000-0001-6481-0537)
Institutions
- HOGENT University of Applied Sciences and Arts (BE)
- Technical University of Cluj-Napoca (RO)
- Ghent University Hospital (BE)
- Polytechnic School of Algiers (DZ)
- Ghent University (BE)
- VIB-UGent Center for Plant Systems Biology (BE)
- Istanbul Technical University (TR)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1016/j.jare.2025.06.047
- Citations
- 2
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 4.38
Funders
- Ministerul Cercetării, Inovării şi Digitalizării
- Fonds Wetenschappelijk Onderzoek
- Bijzonder Onderzoeksfonds UGent
- H2020 European Research Council