Limited additional value of dual-layer spectral 4DCT compared with conventional 4DCT for preoperative localization in primary hyperparathyroidism

Dual-layer spectral-CT is comparable or inferior to conventional CT in tissue differentiation. VNC reconstructions are not recommended as a substitute for true non-contrast due to inconsistent results. In this cohort, dual-layer spectral 4DCT did not demonstrate clear clinical advantage; further validation is warranted.

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Publication Details

Journal
European Journal of Radiology Open
Published
2025-06-24
DOI
https://doi.org/10.1016/j.ejro.2025.100669
Primary Topic
Advanced X-ray and CT Imaging
Type
article
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article

Limited additional value of dual-layer spectral 4DCT compared with conventional 4DCT for preoperative localization in primary hyperparathyroidism

Wim J.G. Oyen, Laura N. Deden, Marie Louise E. Bernsen, Cornelis H. Slump et al.
1 links
European Journal of Radiology Open
Advanced X-ray and CT Imaging
article

Limited additional value of dual-layer spectral 4DCT compared with conventional 4DCT for preoperative localization in primary hyperparathyroidism

Wim J.G. Oyen, Laura N. Deden, Marie Louise E. Bernsen, Cornelis H. Slump, F.B.M. Joosten, J Król, Tessa Veerbeek
article en

Abstract

Dual-layer spectral-CT is comparable or inferior to conventional CT in tissue differentiation. VNC reconstructions are not recommended as a substitute for true non-contrast due to inconsistent results. In this cohort, dual-layer spectral 4DCT did not demonstrate clear clinical advantage; further validation is warranted.

European Journal of Radiology OpenVol. 15
Humanitas University (IT), Radboud University Nijmegen (NL), Radboud University Medical Center (NL), Rijnstate Hospital (NL), University of Twente (NL)
Zero hunger
Openalex Percentile: Top 86%
Advanced X-ray and CT Imaging
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Limited additional value of dual-layer spectral 4DCT compared with conventional 4DCT for preoperative localization in primary hyperparathyroidism — Wim J.G. Oyen, Laura N. Deden, et al. · European Journal of Radiology Open (2025) | TGRS Research Map | TGRS