Involvement of the Programmed Death 1/Programmed Death Ligand 1 Pathway in the Immune Microenvironment of Chronic Periapical Lesions
We demonstrated the involvement of PD-L1 and PD-1 in the regulation of T cell immunity in chronic periapical lesions. These findings suggest that activating the PD-1/PD-L1 pathway is a potential therapeutic strategy for chronic periapical lesions.
Authors
- Bang‐Hun Hyun (ORCID: https://orcid.org/0000-0002-3429-3425)
- Kyu‐Young Oh (ORCID: https://orcid.org/0000-0001-5328-0905)
- Yujin Song (ORCID: https://orcid.org/0000-0003-2310-8551)
- S.B. Park (ORCID: https://orcid.org/0000-0002-8471-3707)
- Huimin Jin (ORCID: https://orcid.org/0000-0001-9290-1401)
Institutions
- Dankook University Hospital (KR)
- Dankook University (KR)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1016/j.identj.2025.100874
- Citations
- 1
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 1.05
Funders
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea