Exploring causal correlations between inflammatory response related genes and Osteoporosis: A Multi-Omics Mendelian Randomization Study

This multi-omics integration study revealed a genetic link between IR and OP, as represented by IR-related genes, and provided new insights into the potential pathogenic mechanisms of OP. Additionally, these identified candidate genes offer avenues for future targeted functional studies aimed at developing appropriate therapeutic interventions and preventing OP.

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Publication Details

Journal
Archives of Medical Science
Published
2025-06-24
DOI
https://doi.org/10.5114/aoms/205243
Primary Topic
Bone Metabolism and Diseases
Type
article
Field-Weighted Citation Impact
0.00

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article

Exploring causal correlations between inflammatory response related genes and Osteoporosis: A Multi-Omics Mendelian Randomization Study

R Y Zhang, Jie Zhao
1 links
Archives of Medical Science
Bone Metabolism and Diseases
article

Exploring causal correlations between inflammatory response related genes and Osteoporosis: A Multi-Omics Mendelian Randomization Study

R Y Zhang, Jie Zhao
article en

Abstract

This multi-omics integration study revealed a genetic link between IR and OP, as represented by IR-related genes, and provided new insights into the potential pathogenic mechanisms of OP. Additionally, these identified candidate genes offer avenues for future targeted functional studies aimed at developing appropriate therapeutic interventions and preventing OP.

Archives of Medical ScienceVol. 21(4)
Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Natural Science Foundation of Shandong Province
Openalex Percentile: Top 87%
Bone Metabolism and Diseases
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