Genetic causal relationship between physical activity and osteoarthritis: a two-sample Mendelian randomization study

The results of this study provide evidence against a genetic causal relationship between PA and KOA, thereby contributing to the understanding of their correlation. However, the study does not rule out the possibility of a relationship through non-genetic mechanisms.

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Publication Details

Journal
Archives of Medical Science
Published
2025-06-24
DOI
https://doi.org/10.5114/aoms/205242
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
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article

Genetic causal relationship between physical activity and osteoarthritis: a two-sample Mendelian randomization study

Yani Su, Jiale Xie, Pengfei Wen, Zhi Yang et al.
1 links
Archives of Medical Science
Osteoarthritis Treatment and Mechanisms
article

Genetic causal relationship between physical activity and osteoarthritis: a two-sample Mendelian randomization study

Yani Su, Jiale Xie, Pengfei Wen, Zhi Yang, Xianjie Wan, Mingyi Yang, Ke Xu, Lin Liu, Peng Xu, Hui Yu
article en

Abstract

The results of this study provide evidence against a genetic causal relationship between PA and KOA, thereby contributing to the understanding of their correlation. However, the study does not rule out the possibility of a relationship through non-genetic mechanisms.

Archives of Medical ScienceVol. 21(5)
Xi'an Honghui Hospital (CN), Xi'an Jiaotong University (CN)
Openalex Percentile: Top 76%
Osteoarthritis Treatment and Mechanisms
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Genetic causal relationship between physical activity and osteoarthritis: a two-sample Mendelian randomization study — Yani Su, Jiale Xie, et al. · Archives of Medical Science (2025) | TGRS Research Map | TGRS