Patritumab Deruxtecan (HER3-DXd; MK-1022) in Non–Small Cell Lung Cancer After Platinum-Based Chemotherapy and Immunotherapy
The previously reported efficacy and safety of HER3-DXd in heavily pretreated patients with <i>EGFR</i>-mutated NSCLC are also observed in those with other NSCLC subtypes and warrant further clinical evaluation.
Authors
- Egbert F. Smit (ORCID: https://orcid.org/0000-0002-7329-6995)
- Xin Su (ORCID: https://orcid.org/0000-0002-8046-3843)
- David Sternberg (ORCID: https://orcid.org/0000-0002-3925-1304)
- Haruyasu Murakami (ORCID: https://orcid.org/0000-0003-2416-546X)
- Erminia Massarelli (ORCID: https://orcid.org/0000-0001-7798-7286)
- Wu‐Chou Su (ORCID: https://orcid.org/0000-0003-2953-4105)
- Hidetoshi Hayashi (ORCID: https://orcid.org/0000-0001-8787-5587)
- Kathryn A. Gold (ORCID: https://orcid.org/0000-0001-5165-4424)
- Sang‐We Kim (ORCID: https://orcid.org/0000-0003-1065-8095)
- Pang‐Dian Fan (ORCID: https://orcid.org/0000-0002-7968-7516)
- Pasi Antero Janne (ORCID: https://orcid.org/0000-0002-7821-4928)
- Melissa L. Johnson (ORCID: https://orcid.org/0000-0001-9874-1314)
- Christina S. Baik (ORCID: https://orcid.org/0009-0007-0822-9060)
- K Landry Truchon
- Masahiro Fujimura
- Makoto Nishio (ORCID: https://orcid.org/0000-0003-4969-4165)
- Conor Steuer (ORCID: https://orcid.org/0000-0001-6528-6319)
- Enriqueta Felip (ORCID: https://orcid.org/0000-0002-7620-0098)
- Dong‐Wan Kim (ORCID: https://orcid.org/0000-0001-5124-7132)
Institutions
- Ulsan College (KR)
- Seattle Cancer Care Alliance (US)
- Emory University (US)
- University of Washington (US)
- UC San Diego Health System (US)
- Asan Medical Center (KR)
- Seoul National University Hospital (KR)
- The Netherlands Cancer Institute (NL)
- University of Ulsan (KR)
- Shizuoka Cancer Center (JP)
- Sarah Cannon (US)
- City of Hope (US)
- Dana-Farber Cancer Institute (US)
- Vall d'Hebron Hospital Universitari (ES)
- Tennessee Oncology (US)
- The Cancer Institute Hospital (JP)
- National Cheng Kung University Hospital (TW)
- Daiichi Sankyo (United States) (US)
- Vall d'Hebron Institute of Oncology (ES)
- Kindai University (JP)
Publication Details
- Journal
- Journal of Clinical Oncology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1200/jco-24-02744
- Citations
- 8
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 12.15