Abrus precatorius (powder) poisoning and recovery

Abrus precatorius contains abrin, the toxin abrin is a dimer consisting of two protein subunits, termed A and B. The B chain facilitates abrin’s entry into a cell by bonding to certain transport proteins on cell membranes, which then transport the toxin into the cell. Once inside the cell, then a chain prevents protein synthesis by inactivating the 28S RNA of the ribosome. One molecule of abrin will inactivate up to 1500 ribosomes per second that cause the inhibition of protein synthesis leading to cell death and further death of an individual.

Authors

Publication Details

Journal
Medicover journal of medicine.
Published
2025-01-01
DOI
https://doi.org/10.4103/mjm.mjm_35_24
Primary Topic
Toxin Mechanisms and Immunotoxins
Type
article
Field-Weighted Citation Impact
0.00
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article

Abrus precatorius (powder) poisoning and recovery

R Sidhu
Medicover journal of medicine.
Toxin Mechanisms and Immunotoxins
article

Abrus precatorius (powder) poisoning and recovery

R Sidhu
article en

Abstract

Abrus precatorius contains abrin, the toxin abrin is a dimer consisting of two protein subunits, termed A and B. The B chain facilitates abrin’s entry into a cell by bonding to certain transport proteins on cell membranes, which then transport the toxin into the cell. Once inside the cell, then a chain prevents protein synthesis by inactivating the 28S RNA of the ribosome. One molecule of abrin will inactivate up to 1500 ribosomes per second that cause the inhibition of protein synthesis leading to cell death and further death of an individual.

Medicover journal of medicine.Vol. 2(1)
Openalex Percentile: Top 84%
Toxin Mechanisms and Immunotoxins
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Abrus precatorius (powder) poisoning and recovery — R Sidhu · Medicover journal of medicine. (2025) | TGRS Research Map | TGRS