Next-Generation Sequencing Techniques to Diagnose Culture-Negative Subacute Native Aortic Endocarditis
Next-generation sequencing might improve diagnosis of infective endocarditis. A case in Switzerland was initially attributed to Solobacterium moorei bacteria. Metagenomic analysis of the affected heart valve detected Streptococcus gordonii, but not S. moorei, illustrating that the results of molecular detection can vary depending on sampling time and anatomic site.
Authors
- Maria‐Christina Zennaro (ORCID: https://orcid.org/0000-0001-5449-9191)
- D. Vetterli
- Virginie Tacchini
- Vladimir Lazarević (ORCID: https://orcid.org/0000-0002-6839-2536)
- Johannes Alexander Lobrinus (ORCID: https://orcid.org/0000-0002-6963-9342)
- Virginie Prendki (ORCID: https://orcid.org/0000-0003-1315-2938)
- Jacques Schrenzel (ORCID: https://orcid.org/0000-0001-5464-7764)
Publication Details
- Journal
- Emerging infectious diseases
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3201/eid3107.241739
- Primary Topic
- Infective Endocarditis Diagnosis and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00