Serum NF-κB-Regulated Biomarkers of Proliferative Lupus Nephritis
We identified the NF-κB-regulated proteins SCF, M-CSF, and IL-2Rα as candidate serum biomarkers for consideration in monitoring LN activity. Our findings also indicate the importance for follow-up mechanistic studies pertaining to these inflammatory mediators.
Authors
- Makayla Brady (ORCID: https://orcid.org/0000-0001-9874-2640)
- Michelle T. Barati (ORCID: https://orcid.org/0000-0002-1318-9901)
- Cristina Arriens (ORCID: https://orcid.org/0000-0002-9546-1664)
- Dawn J. Caster
- Kristen Overton (ORCID: https://orcid.org/0000-0001-6726-5722)
- Steven Mathis (ORCID: https://orcid.org/0000-0001-7704-1220)
- Rebecca Lightman (ORCID: https://orcid.org/0000-0003-0199-1953)
- Nicholas A. Shoctor
- David W. Powell (ORCID: https://orcid.org/0000-0003-4309-7052)
- Madhavi J. Rane (ORCID: https://orcid.org/0000-0003-0452-2693)
- Shweta Tandon (ORCID: https://orcid.org/0000-0001-7488-5583)
Institutions
- University of Louisville (US)
- Oklahoma Medical Research Foundation (US)
Publication Details
- Journal
- Glomerular Diseases
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1159/000547044
- Citations
- 1
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 1.67
Funders
- University of Louisville
- National Institutes of Health
- National Institute of General Medical Sciences
- National Institute of Diabetes and Digestive and Kidney Diseases