Genome-wide association and linkage analysis of histidine-rich glycoprotein identifies common variants associated with plasma histidine-rich glycoprotein concentrations
The results of this genome-wide association study, investigating HRG concentration variation in a healthy population, provide new insights into the genetic control of circulating HRG concentrations and generate data for colocalization and Mendelian randomization studies.
Authors
- Cherie Teney
- Ayse Bilge Ozel (ORCID: https://orcid.org/0000-0002-1112-4258)
- Karl C. Desch (ORCID: https://orcid.org/0000-0003-0392-4033)
- Beth McGee (ORCID: https://orcid.org/0000-0001-5786-7164)
- Mary Underwood (ORCID: https://orcid.org/0000-0003-4868-6999)
- Colin A. Kretz (ORCID: https://orcid.org/0000-0001-7979-7603)
- Rida Malik (ORCID: https://orcid.org/0000-0001-7118-8715)
- Jeffrey Ian Weitz (ORCID: https://orcid.org/0000-0002-1092-7550)
- D. R. Siemieniak
- Tanay Deepak
Institutions
- University of Michigan (US)
- Thrombosis and Atherosclerosis Research Institute (CA)
- McMaster University (CA)
Publication Details
- Journal
- Research and Practice in Thrombosis and Haemostasis
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1016/j.rpth.2025.102955
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- National Institutes of Health
- National Heart, Lung, and Blood Institute