Prophylactic Rectal ESD (Endoscopic Submucosal Dissection) Defect Closure and Post-ESD Clinical Outcomes: An International Multi-Center Study (with Video)
Prophylactic closure of rectal ESD defects leads to significantly less overnight hospital observation. Anticoagulant use, NICE 3 lesions and incomplete resections had significantly higher DAE within 2 weeks. While defect closure did not significantly reduce the overall DAE, selective prophylactic defect closure in high-risk groups will need to be studied in larger samples.
Authors
- Sumant Inamdar (ORCID: https://orcid.org/0000-0002-1002-2823)
- Michele Francesco Chiappetta (ORCID: https://orcid.org/0000-0002-8382-9687)
- Federico Barbaro (ORCID: https://orcid.org/0000-0002-7928-3757)
- Antonio Mendoza Ladd (ORCID: https://orcid.org/0000-0002-8013-3545)
- Alexander Schlachterman (ORCID: https://orcid.org/0000-0002-0633-7611)
- Galen Leung (ORCID: https://orcid.org/0000-0002-2803-7441)
- Saowanee Ngamruengphong (ORCID: https://orcid.org/0000-0003-0855-7500)
- Fiona Milne (ORCID: https://orcid.org/0000-0003-4955-2597)
- Jonathan S. Steinberg
- Yasi Xiao (ORCID: https://orcid.org/0000-0002-2471-0133)
- Edward J. Despott (ORCID: https://orcid.org/0000-0001-6311-3692)
- Jason Samarasena (ORCID: https://orcid.org/0000-0002-2981-3078)
- Robert Bechara (ORCID: https://orcid.org/0000-0002-4543-5580)
- Laura Lucaciu (ORCID: https://orcid.org/0000-0002-6310-2384)
- Mohammad Bilal (ORCID: https://orcid.org/0000-0002-1784-212X)
- Frances Dang (ORCID: https://orcid.org/0000-0002-7068-3156)
- Yutaka Tomizawa (ORCID: https://orcid.org/0009-0000-9758-4441)
- Rahul Karna (ORCID: https://orcid.org/0000-0002-6775-0776)
- Pranita Madaka
- Reygenald D Ines
- Celestina Tolosa
- Anand Kumar (ORCID: https://orcid.org/0000-0002-4339-2353)
- Joria Le
- Thomas E. Kowalski
- Faisal Kamal
- Amer Alsamman
- Lionel D’Souza (ORCID: https://orcid.org/0009-0006-8031-2822)
Institutions
- Università Cattolica del Sacro Cuore (IT)
- University of Minnesota (US)
- Johns Hopkins University (US)
- University of Washington (US)
- University of California, Irvine (US)
- Queen's University (CA)
- Thomas Jefferson University Hospital (US)
- Johns Hopkins Medicine (US)
- The Royal Free Hospital (GB)
- Stony Brook University Hospital (US)
- Agostino Gemelli University Polyclinic (IT)
- University of California, Irvine Medical Center (US)
- Minneapolis VA Medical Center (US)
- Johns Hopkins Hospital (US)
- Jefferson Hospital (US)
- Kingston Health Sciences Centre (CA)
- University College London (GB)
- Drexel University (US)
- University of Pennsylvania (US)
- University of Arkansas for Medical Sciences (US)
- University of California, Davis (US)
Publication Details
- Journal
- Digestive Diseases and Sciences
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1007/s10620-025-09123-7
- Citations
- 4
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 6.07