Association of dietary inflammatory index with liver fibrosis and fatty liver index in a population with metabolic dysfunction-associated steatotic liver disease: A cross-sectional study
In U.S. adults with MASLD, no significant association was found between DII and the risk of liver fibrosis or elevated FLI. Although DII is linked to various chronic diseases, its role in MASLD appears limited and non-specific, particularly in capturing intermittent disease progression. No mediating effect of SII was observed. These findings underscore the importance of carefully considering dietary factors in the clinical evaluation of MASLD progression. The potential relationship between diet and liver disease progression warrants further investigation.
Authors
- Zi-Tong Sang (ORCID: https://orcid.org/0009-0007-0972-4450)
- Peng Sun (ORCID: https://orcid.org/0000-0002-9169-5914)
- Tiejun Liu (ORCID: https://orcid.org/0000-0001-5028-1304)
- Han Wang (ORCID: https://orcid.org/0000-0002-3420-2116)
- Ruolin Wang (ORCID: https://orcid.org/0000-0002-0348-5256)
- Xupeng Huang
- Houbo Deng (ORCID: https://orcid.org/0000-0002-2310-2013)
- Yan Leng (ORCID: https://orcid.org/0000-0002-2839-3526)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Changchun University of Chinese Medicine (CN)
- The Affiliated Hospital to Changchun University of Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3389/fnut.2025.1594192
- Citations
- 3
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 4.06