Pediatric-Type Diffuse Low-Grade Gliomas with <i>MYB</i> Alterations: Neuroimaging of the Diffuse Astrocytomas, <i>MYB-</i> or <i>MYBL1</i> -Altered
Imaging features of DA-MYB in children are variable, and the fireworks sign was identified only in a subset of patients. It was usually present in patients with large hemispheric tumors but was also observed in brainstem lesions. Diffusion restriction was consistently absent and enhancement infrequent. A T2 FLAIR mismatch was seen in >50% of patients.
Authors
- Volodia Dangouloff‐Ros (ORCID: https://orcid.org/0000-0003-1260-5886)
- Sniya Sudhakar (ORCID: https://orcid.org/0000-0002-7632-9705)
- Darren Hargrave (ORCID: https://orcid.org/0000-0001-8219-9807)
- Brigitte Bison (ORCID: https://orcid.org/0000-0001-5849-8671)
- Lars Behrens (ORCID: https://orcid.org/0000-0002-3221-6055)
- Pablo Hernáiz Driever (ORCID: https://orcid.org/0000-0003-3135-3872)
- Cesar Alves (ORCID: https://orcid.org/0000-0001-5877-9086)
- Maarit Palomäki
- Giovanni Morana (ORCID: https://orcid.org/0000-0001-8707-5969)
- Svea Horn
- Kshitij Mankad (ORCID: https://orcid.org/0000-0001-5979-9337)
- Thomas S. Jacques (ORCID: https://orcid.org/0000-0002-7833-2158)
- F. Coppola (ORCID: https://orcid.org/0009-0001-6661-8474)
- Maarten Lequin
- Ulrike Löbel (ORCID: https://orcid.org/0000-0001-9844-3464)
- Anna Tietze (ORCID: https://orcid.org/0000-0002-2601-9055)
Institutions
- Hôpital Necker-Enfants Malades (FR)
- Boston Children's Hospital (US)
- University of Helsinki (FI)
- Université Paris Cité (FR)
- Great Ormond Street Hospital (GB)
- Great Ormond Street Hospital for Children NHS Foundation Trust (GB)
- Helsinki University Hospital (FI)
- University Hospital Augsburg (DE)
- Humboldt-Universität zu Berlin (DE)
- Azienda Ospedaliera Citta' della Salute e della Scienza di Torino (IT)
- Sorbonne Paris Cité (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Neuroscience Institute (IT)
- Texas Children's Hospital (US)
- Society of Paediatric Oncology and Haematology (DE)
- University College London (GB)
- University of Turin (IT)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- American Journal of Neuroradiology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3174/ajnr.a8894
- Citations
- 2
- Primary Topic
- Glioma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 3.25