The causal effect of smoking on psychiatric disorders: an examination of brain volume as a potential pathway
While these findings are limited by characteristics of the included summary statistics (e.g. sample size), we conclude that brain volume of these areas is unlikely to explain a substantial part of any effect of smoking on psychiatric disorders. Nevertheless, genetic methods are valuable tools for exploring other potential mechanisms, such as brain functional connectivity, foregoing the need to collect all phenotypes in one dataset.
Authors
- Dirk J. A. Smit (ORCID: https://orcid.org/0000-0001-8301-8860)
- Marcus R. Munafò (ORCID: https://orcid.org/0000-0002-4049-993X)
- Margot P. van de Weijer (ORCID: https://orcid.org/0000-0001-9720-9481)
- Jentien M. Vermeulen (ORCID: https://orcid.org/0000-0002-6245-6498)
- Jorien L. Treur (ORCID: https://orcid.org/0000-0003-4370-3390)
- Robyn E. Wootton (ORCID: https://orcid.org/0000-0003-3961-3202)
- Anaïs B Thijssen (ORCID: https://orcid.org/0000-0001-6782-3608)
- Karin J. H. Verweij (ORCID: https://orcid.org/0000-0001-9868-7821)
- Guido van Wingen (ORCID: https://orcid.org/0000-0003-3076-5891)
- Adrià Túnez (ORCID: https://orcid.org/0000-0002-4208-472X)
- Shu Liu (ORCID: https://orcid.org/0000-0001-8312-0080)
Institutions
- At Bristol (GB)
- University of Bristol (GB)
- Lovisenberg Diakonale Høgskole (NO)
- University of Amsterdam (NL)
Publication Details
- Journal
- Psychological Medicine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1017/s0033291725100561
- Citations
- 3
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 5.45