Dual-route levofloxacin delivery following revision surgery: a synergistic intravenous/intra-articular strategy for enhanced bactericidal effect against prosthetic Pseudomonas aeruginosa infections
Combined IV and IA levofloxacin effectively target PA biofilms in PJI without significant safety concerns, offering a promising therapeutic strategy for PA-induced PJI.
Authors
- Tao Zhang (ORCID: https://orcid.org/0000-0003-1048-4443)
- Xinyu Li (ORCID: https://orcid.org/0000-0001-7203-7417)
- Dehua Wang (ORCID: https://orcid.org/0000-0001-6420-7201)
- Mengqiu Li (ORCID: https://orcid.org/0000-0002-1905-9497)
- Yan Liy (ORCID: https://orcid.org/0000-0001-6155-0389)
Institutions
- The Affiliated Yongchuan Hospital of Chongqing Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1097/js9.0000000000002712
- Primary Topic
- Orthopedic Infections and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00