Combined Pipeline Embolization and Coiling of an Intracranial Aneurysm in Marfan Syndrome: A Case Report and Literature Review

This is the first case of combined PED and coiling for an intracranial aneurysm in Marfan syndrome. This dual approach may offer safer and more effective treatment than traditional methods. In addition, the formation of de novo aneurysms underscores the importance of long-term angiographic follow-up in patients with <i>FBN1</i> mutations to monitor for evolving vascular pathology. These findings warrant further investigation into identifying a genetic link between <i>FBN1</i> mutations and cerebrovascular pathology.

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Publication Details

Journal
Neurosurgery Open
Published
2025-06-24
DOI
https://doi.org/10.1227/neuprac.0000000000000136
Primary Topic
Aortic Disease and Treatment Approaches
Type
article
Field-Weighted Citation Impact
0.00
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article

Combined Pipeline Embolization and Coiling of an Intracranial Aneurysm in Marfan Syndrome: A Case Report and Literature Review

Eytan Raz, Maksim Shapiro, Howard A. Riina, Vera Sharashidze et al.
Neurosurgery Open
Aortic Disease and Treatment Approaches
article

Combined Pipeline Embolization and Coiling of an Intracranial Aneurysm in Marfan Syndrome: A Case Report and Literature Review

Eytan Raz, Maksim Shapiro, Howard A. Riina, Vera Sharashidze, Erez Nossek, Eric A. Grin
article en

Abstract

This is the first case of combined PED and coiling for an intracranial aneurysm in Marfan syndrome. This dual approach may offer safer and more effective treatment than traditional methods. In addition, the formation of de novo aneurysms underscores the importance of long-term angiographic follow-up in patients with <i>FBN1</i> mutations to monitor for evolving vascular pathology. These findings warrant further investigation into identifying a genetic link between <i>FBN1</i> mutations and cerebrovascular pathology.

Neurosurgery OpenVol. 6(3)
New York University (US)
Openalex Percentile: Top 76%
Aortic Disease and Treatment Approaches
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