Predicting brain health in community-dwelling elderly populations by integrating Gaussian mixture model and plasma biomarkers
Our study indicated that the combination of GMM and plasma biomarkers for community screening shows promising potential in monitoring brain health among older adults without dementia. P-tau217 exhibited the best predictive value among the three plasma biomarkers.
Authors
- T. J. Zhu (ORCID: https://orcid.org/0009-0006-4338-8991)
- Zhiming Lu (ORCID: https://orcid.org/0000-0003-1228-5739)
- Yue Wang (ORCID: https://orcid.org/0000-0002-0456-1273)
- Qian Cheng (ORCID: https://orcid.org/0000-0003-3621-5743)
- Pengfei Zhang (ORCID: https://orcid.org/0000-0002-2828-9067)
- Xiaolin Cui
Institutions
- Shandong University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Journal of Alzheimer s Disease Reports
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1177/25424823251331110
- Citations
- 1
- Primary Topic
- Dementia and Cognitive Impairment Research
- Type
- article
- Field-Weighted Citation Impact
- 1.47
Funders
- National Natural Science Foundation of China