Longitudinal NMR-based Metabolomics Analysis of Male Mountain Ultramarathon Runners: New Perspectives for Athletes Monitoring and Injury Prevention
In this study, we propose an NMR-based metabolomics strategy to assess exercise-associated metabolic changes during and after events such as the Tor des Géants. Using state-of-the-art data representation methods specific to metabolomics analysis, we demonstrated that such a methodology can provide a unique view of the biology associated with such extreme conditions. As this approach provides unique insights into the biology of extreme exercise, it holds promise for the development of new tools for athlete management.
Authors
- Philippe Massonnet (ORCID: https://orcid.org/0000-0002-1326-692X)
- Justine Demeuse (ORCID: https://orcid.org/0009-0003-9791-7842)
- Elodie Grifnée
- Loreen Huyghebaert (ORCID: https://orcid.org/0009-0006-6737-1270)
- Thomas Dubrowski
- Eric Brevers
- Grégoire Paul Millet (ORCID: https://orcid.org/0000-0001-8081-4423)
- Stéphanie Peeters
- Pascal De Tullio (ORCID: https://orcid.org/0000-0002-4234-4587)
- Étienne Cavalier (ORCID: https://orcid.org/0000-0003-0947-2226)
- Matthieu Schoumacher
- Caroline Le Goff (ORCID: https://orcid.org/0000-0001-7816-3705)
- Pierre Croisille (ORCID: https://orcid.org/0000-0003-4019-3460)
- Jean‐François Kaux (ORCID: https://orcid.org/0000-0003-1939-3652)
- Joy Ledeck
- Manon Campas
- Arianna Cirillo
- Jessica Nguyen
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- University of Liège (BE)
- Centre Hospitalier Universitaire de Liège (BE)
- International Federation of Sports Medicine (CH)
- University of Lausanne (CH)
Publication Details
- Journal
- Sports Medicine - Open
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1186/s40798-025-00879-w
- Citations
- 3
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.42
Funders
- Fonds Léon Fredericq