Effectiveness of regular oat β-glucan–enriched bread compared with whole-grain wheat bread on long-term glycemic control in adults at risk of type 2 diabetes: a randomized controlled trial
Contrary to expectations from efficacy studies, this effectiveness trial does not support the metabolic benefits of oat-derived β-glucan-enriched bread under real-life conditions. A simple bread replacement may not be sufficient to improve glucose homeostasis in individuals at risk of type 2 diabetes. This trial was registered with clinicaltrials.gov as NCT04994327.
Authors
- Jutta Dierkes (ORCID: https://orcid.org/0000-0003-0663-877X)
- Paula Varela (ORCID: https://orcid.org/0000-0003-2473-8678)
- Ulrike Spielau
- Ingrid Revheim (ORCID: https://orcid.org/0000-0002-1394-759X)
- Anne Rieder (ORCID: https://orcid.org/0000-0001-7885-9104)
- Alena Schadow (ORCID: https://orcid.org/0009-0004-4300-9387)
- Simon Ballance (ORCID: https://orcid.org/0000-0001-7189-7212)
- Hanne Rosendahl-Riise (ORCID: https://orcid.org/0000-0002-1497-416X)
- Anette E. Buyken (ORCID: https://orcid.org/0000-0002-4301-1127)
- Thérése Hjorth (ORCID: https://orcid.org/0000-0001-6868-833X)
- Rikard Landberg (ORCID: https://orcid.org/0000-0002-6399-7608)
- Klara Meyer
- Antje Koerner
Institutions
- Paderborn University (DE)
- Nofima (NO)
- University Hospital Leipzig (DE)
- University of Bergen (NO)
- Chalmers University of Technology (SE)
Publication Details
- Journal
- American Journal of Clinical Nutrition
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1016/j.ajcnut.2025.06.018
- Citations
- 3
- Primary Topic
- Food composition and properties
- Type
- article
- Field-Weighted Citation Impact
- 3.36