Chronic tophaceous gout presenting with severe hypercalcemia - A rare clinical entity
Gout is an inflammatory arthritis caused by the accumulation of monosodium urate crystals within the synovial fluid and surrounding tissues. This condition is closely linked to hyperuricaemia, a serum urate concentration of 6.8 mg/dL or higher. If hyperuricaemia is not properly managed, the disease may progress to chronic tophaceous gout, which involves long-term joint damage and deposition of crystal aggregates (tophi) in joints and soft tissues. In this case report, we describe the case of a 62-year-old male who presented with altered mental status, generalised weakness, poor oral intake and diffuse body pain. Laboratory tests revealed severe hypercalcaemia, which is a rare presentation. The patient was treated with intravenous saline hydration, calcitonin and prednisone, which improved kidney function and normalised calcium levels.
Authors
- Jagmeet Singh (ORCID: https://orcid.org/0000-0001-7179-1020)
- Ishan Garg (ORCID: https://orcid.org/0000-0002-4258-0192)
- Vikas Garg (ORCID: https://orcid.org/0000-0001-6886-3003)
- Rohit Raina (ORCID: https://orcid.org/0000-0002-1942-9072)
Institutions
- Central University of Punjab (IN)
- All India Institute of Medical Sciences Raipur (IN)
- All India Institute of Medical Sciences Bhopal (IN)
- Public Works Department Buildings and Roads (IN)
- All India Institute of Medical Sciences (IN)
Publication Details
- Journal
- Current Medicine Research and Practice
- Published
- 2025-05-01
- DOI
- https://doi.org/10.4103/cmrp.cmrp_23_25
- Citations
- 1
- Primary Topic
- Gout, Hyperuricemia, Uric Acid
- Type
- article
- Field-Weighted Citation Impact
- 1.43