Adverse cutaneous drug reaction due to possible lorazepam in a 12-year-old patient with Hunter Syndrome

Benzodiazepines may cause adverse cutaneous reactions in about 0.3% of patients, with lorazepam linked to hypersensitivity and exanthematous eruptions in adults.Lorazepam, an intermediate-acting benzodiazepine, is commonly prescribed for anxiety and status epilepticus, and its pharmacological effects are mediated by gamma-aminobutyric acid (GABA).This report presents a lorazepam-induced skin reaction in a 12-year-old male patient with Hunter syndrome, which improved after discontinuation of lorazepam therapy.