Effect of yeast supplemented with selenium or zinc on some antioxidant indices and liver and kidney functions in local Iraqi goats

The purpose of the research was to investigate the effect of yeast supplemented with selenium or zinc on the antioxidant profile of local Iraqi goats. The study utilized seventeen female goats with an average body weight (BW) of 37.5 ± 2.5 kg and an average age of 2-2.5 years. The animals were randomly assigned to three groups: group I contained five goats, while groups II and III contained six goats. The control group (Group I) was not treated, while Group II was given a dose of selenium-supplemented yeast (Saccharomyces cerevisiae-selenium) at 0.03 g/kg/BW. Group III was offered a dose of zinc-supplemented yeast (Saccharomyces cerevisiae-zinc) at 0.2 g/kg/BW. The samples were administered orally to the animals for 45 days after being dissolved in 30 ml of distilled water. The changes in the level of liver and antioxidant enzymes were determined by collecting blood samples from the jugular vein on the first day and the 45th day. The result showed the Y+Se and Y+Zn treatments significantly reduced malondialdehyde, AST, and ALT in comparison to the control treatment (P < 0.05). However, the GPx levels of the animals that received the treatment diets increased. In both treatment treatments, there was a significant decrease in Creatinine and Urea. The treatments exhibited decreased indications of globulin and albumin in comparison to the control treatment. In conclusion, the results suggest that the serum antioxidant activity of goats was not only improved but also the lipid peroxidation was reduced by dietary yeast supplemented with selenium (Saccharomyces cerevisiae-selenium).