Malignant peripheral nerve sheath tumor in early childhood: a case report of a diagnostic challenge
This case highlights the challenges associated with MPNST in pediatric NF1. Both surgery and chemotherapy have been shown to enhance outcomes. Ongoing monitoring is crucial, and additional research on MEK inhibitors and genetic profiling is imperative for tailoring treatment strategies.
Authors
- Jianqing Liang (ORCID: https://orcid.org/0000-0002-1461-2329)
- Xin Zhang (ORCID: https://orcid.org/0000-0002-4026-4284)
- Wenbin Guan
Institutions
- XinHua Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3389/fonc.2025.1609477
- Citations
- 1
- Primary Topic
- Neurofibromatosis and Schwannoma Cases
- Type
- article
- Field-Weighted Citation Impact
- 1.39
Funders
- National Natural Science Foundation of China
- Shanghai Jiao Tong University
- School of Medicine, Shanghai Jiao Tong University