Acute effect of statins on vascular reactivity in maternal and placental arteries from pregnancies complicated by preeclampsia
In conclusion, this study did not demonstrate an effect on vascular reactivity of maternal systemic or fetoplacental arteries following acute treatment of statins. Future studies investigating the effect of longer-term statin exposure on maternal and fetoplacental vascular reactivity may help towards treatment strategies for vascular dysfunction in PE-affected patients.
Authors
- Chinedu Agwu
- Jenny Myers (ORCID: https://orcid.org/0000-0003-0913-2096)
- Mark Wareing (ORCID: https://orcid.org/0000-0002-1333-0899)
- Mark Dilworth (ORCID: https://orcid.org/0000-0002-7106-7451)
Institutions
- Manchester Academic Health Science Centre (GB)
- University of Manchester (GB)
- Manchester University NHS Foundation Trust (GB)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3389/fphys.2025.1575128
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00