Molecular insights into glioblastoma progression: role of CHCHD2P9 in tumor heterogeneity and prognosis
CHCHD2P9 is significantly overexpressed in glioma patients, and its differential expression plays a crucial role in regulating glioma cell proliferation and migration. A CHCHD2P9-based risk model holds promise as both a prognostic biomarker and a potential therapeutic target, providing novel insights into the pathogenesis of gliomas and opening avenues for personalized treatment strategies.
Authors
- Tian-Hang Yu
- Jiaxin Zhao
- Jia Ke (ORCID: https://orcid.org/0000-0002-5053-038X)
- Jiyuan Ke (ORCID: https://orcid.org/0000-0002-2415-2696)
- Yanyu Ding
- Cunzhi Wang
- Mengyu Zhao
- Xiaoling Zhou (ORCID: https://orcid.org/0000-0002-5519-3431)
- Yucai Wang (ORCID: https://orcid.org/0000-0002-1576-8341)
- Huabao Cai
- Zhijie Zhao
- Lizhi Xiao
Institutions
- University of Science and Technology of China (CN)
- Anhui Medical University (CN)
- Shanghai Ninth People's Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- National Science Centre (PL)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3389/fimmu.2025.1581850
- Citations
- 5
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Anhui Medical University