Case Report: Two cases of IgG4-related kidney disease with monoclonal gammopathy

Case 1 was diagnosed with IgG4-TIN combined with MGRS, which showed significant renal and hematological improvement after corticosteroid therapy. Case 2 was diagnosed as secondary membranous nephropathy combined with MGUS, but IgG4-MN cannot be ruled out. His renal function improved with methylprednisolone and rituximab treatment, but the M-protein persisted. We review the related diagnosis and treatment to provide more information for clinical practice.

Authors

Institutions

Publication Details

Journal
Frontiers in Immunology
Published
2025-06-24
DOI
https://doi.org/10.3389/fimmu.2025.1539441
Citations
1
Primary Topic
IgG4-Related and Inflammatory Diseases
Type
article
Field-Weighted Citation Impact
1.67
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Case Report: Two cases of IgG4-related kidney disease with monoclonal gammopathy

Pao Xu, Qian Dong, Jiang Liu, Xuanli Tang
1 citations
Frontiers in Immunology
IgG4-Related and Inflammatory Diseases
1.67
article

Case Report: Two cases of IgG4-related kidney disease with monoclonal gammopathy

Pao Xu, Qian Dong, Jiang Liu, Xuanli Tang
article en
1 citations

Abstract

Case 1 was diagnosed with IgG4-TIN combined with MGRS, which showed significant renal and hematological improvement after corticosteroid therapy. Case 2 was diagnosed as secondary membranous nephropathy combined with MGUS, but IgG4-MN cannot be ruled out. His renal function improved with methylprednisolone and rituximab treatment, but the M-protein persisted. We review the related diagnosis and treatment to provide more information for clinical practice.

Frontiers in ImmunologyVol. 16
Ningbo Medical Center Lihuili Hospital (CN), Hangzhou Hospital of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 16%
IgG4-Related and Inflammatory Diseases
1.67
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.