Case Report: Two cases of IgG4-related kidney disease with monoclonal gammopathy
Case 1 was diagnosed with IgG4-TIN combined with MGRS, which showed significant renal and hematological improvement after corticosteroid therapy. Case 2 was diagnosed as secondary membranous nephropathy combined with MGUS, but IgG4-MN cannot be ruled out. His renal function improved with methylprednisolone and rituximab treatment, but the M-protein persisted. We review the related diagnosis and treatment to provide more information for clinical practice.
Authors
- Pao Xu (ORCID: https://orcid.org/0000-0001-7007-8530)
- Qian Dong (ORCID: https://orcid.org/0000-0002-2028-9046)
- Jiang Liu (ORCID: https://orcid.org/0000-0001-6281-6505)
- Xuanli Tang
Institutions
- Ningbo Medical Center Lihuili Hospital (CN)
- Hangzhou Hospital of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3389/fimmu.2025.1539441
- Citations
- 1
- Primary Topic
- IgG4-Related and Inflammatory Diseases
- Type
- article
- Field-Weighted Citation Impact
- 1.67