Targeted drug delivery based on multifunctional dendrimer nanosystems.
Targeted delivery of drugs based on dendrimers has a number of advantages for the treatment of cancer. The drug is delivered to specific tissues and organs, thereby minimizing the undesirable effect on healthy cells. Nanoparticles not only reduce the toxicity of anticancer drugs, but also increase their bioavailability and stability in the body. Dendrimers are considered the most promising as drug delivery vehicles due to their non-immunogenicity and controlled synthesis. They have shown their effectiveness in many areas of biology and medicine, namely chemotherapy, vaccine development, and delivery of genetic material. This article provides an overview of multifunctional dendrimer nanosystems that can be used for drug delivery in the treatment and diagnosis of cancer.
Authors
- Sabina Gayibova (ORCID: https://orcid.org/0000-0002-8373-5234)
- Vadim V. Shmanai (ORCID: https://orcid.org/0000-0003-1775-8101)
- V. A. Zhogla
- E. Bletsko
- S. Shcharbina
Institutions
- Weatherford College (US)
Publication Details
- Journal
- Science and Innovations
- Published
- 2025-06-21
- DOI
- https://doi.org/10.29235/1818-9857-2025-5-78-83
- Primary Topic
- Dendrimers and Hyperbranched Polymers
- Type
- article
- Field-Weighted Citation Impact
- 0.00