The Potential Benefits of a Novel Food Supplement Based on Cannabis Sativa, Boswellia, and Fish Oil for Pain and Inflammation in Physical Activity: Unraveling the Role of Orexin-A Modulation
Flector Softgel FS Integratore may be effective in reducing joint pain and systemic inflammation while supporting metabolic health in active adults. These effects may involve indirect modulation of orexin-A, though the exact mechanisms remain to be clarified. Despite the promising results, conclusions regarding efficacy in comparison with NSAIDs should be approached with caution in the absence of a pharmacological control group. Further studies with larger samples and a longer duration are needed.
Authors
- Salvatore Allocca
- Marco La Marra (ORCID: https://orcid.org/0000-0001-7488-8493)
- Girolamo Di Maio (ORCID: https://orcid.org/0000-0001-6305-2092)
- Fiorenzo Moscatelli (ORCID: https://orcid.org/0000-0003-1274-0332)
- Marcellino Monda (ORCID: https://orcid.org/0000-0002-7184-218X)
- Chiara Schiraldi (ORCID: https://orcid.org/0000-0002-1066-843X)
- Vincenzo Monda (ORCID: https://orcid.org/0000-0002-6083-5814)
- Maria Casillo (ORCID: https://orcid.org/0009-0001-7212-0285)
- Valentina Vassallo (ORCID: https://orcid.org/0000-0001-6891-9724)
- Cristina Scavone (ORCID: https://orcid.org/0000-0002-9216-922X)
- Antonietta Monda (ORCID: https://orcid.org/0009-0009-8422-3837)
- Giovanni Messina (ORCID: https://orcid.org/0000-0002-1730-7063)
- Antonietta Messina (ORCID: https://orcid.org/0000-0001-8343-432X)
- Rita Polito (ORCID: https://orcid.org/0000-0003-1313-2574)
- Francesco Taturi
Institutions
- Parthenope University of Naples (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- San Raffaele University of Rome (IT)
- University Niccolò Cusano (IT)
- Pegaso University (IT)
- Link Campus University (IT)
Publication Details
- Journal
- Sports
- Published
- 2025-06-22
- DOI
- https://doi.org/10.3390/sports13070199
- Citations
- 3
- Primary Topic
- Pharmacological Effects of Medicinal Plants
- Type
- article
- Field-Weighted Citation Impact
- 4.18