AVM-associated epilepsy: current state of the problem

Epileptic seizures occur in 20–25 % of patients with cerebral arteriovenous malformations (AVMs) and are often resistant to both surgical and conservative treatment methods. This literature review provides an analysis of current data on the epidemiology, diagnosis, and treatment of epileptic syndrome in patients with cerebral arteriovenous malformations. Over 100 literature sources available in the PubMed, eLibrary.ru, Medscape, Cochrane Library, and Medical NDX databases were analyzed as part of the study. To reflect the most up-to-date information, primary focus was placed on data published between 2018 and 2023. Special attention in the review is given to modern diagnostic approaches, including the use of neuroimaging and electroencephalography, as well as the latest treatment methods such as stereotactic radiosurgery, endovascular interventions, and combined therapeutic strategies. Factors influencing treatment effectiveness, including the location and size of the AVMs, as well as the clinical course of the epileptic syndrome, are discussed. The review highlights the prospects for further research in this field, aimed at improving patients’ quality of life and reducing the frequency of seizure recurrence. The review emphasizes the need for a multidisciplinary approach to managing patients with cerebral AVMs, as well as the importance of individualized treatment tailored to the specifics of each clinical case.