Synthesis of 6-methoxy-2-methyl-2-(4-methylpent-3-en-1-yl)chroman-4-one via Kabbe Condensation
Apparently, many students spend a lot of time doing column chromatography, and in many cases they describe the process as "difficult", "time-consuming", or "tedious".Often, they would collect numerous fractions, use large amount of solvents even for scales ~100 mg, and routinely spend more than 1 hr or multiple hours just on one column.
Authors
- Stephen A. Chamness
Publication Details
- Journal
- Organic Syntheses
- Published
- 2025-01-01
- DOI
- https://doi.org/10.15227/orgsyn.102.0335
- Citations
- 1
- Primary Topic
- Synthesis of Organic Compounds
- Type
- article
- Field-Weighted Citation Impact
- 1.39