3D Molecular Docking Study of Drug-Drug Interactions Between Antidepressants and Immunosuppressive Drugs
Drug-Drug Interactions (DDIs) are an issue that cannot be ignored in clinical treatment. With the improvement of people's living standards and the evolution of the disease spectrum, the relationship between emotions and the immune system has gradually attracted attention. Among them, mood swings can significantly affect the function of the immune system, and disorders of the immune system may also cause mood disorders. Therefore, the interaction between antidepressants and immunosuppressive drugs has important research value. This article deeply analyzes the interaction strength of these two types of drugs to assess their potential risks, thereby optimizing treatment plans and reducing adverse reactions. At the same time, 3D imaging technology is used to more intuitively display the binding position and action intensity of drugs at the target, providing strong support for clinical decision-making and helping to achieve safer and more personalized combined treatment plans.
Authors
- Xi Wei Wang
- Zheng Yang Zhang
- Tie Hua Zhou (ORCID: https://orcid.org/0000-0002-3258-0244)
- Ling Wang (ORCID: https://orcid.org/0000-0001-8964-6454)
Institutions
- Northeast Electric Power University (CN)
Publication Details
- Published
- 2025-05-05
- DOI
- https://doi.org/10.1109/cscwd64889.2025.11033536
- Citations
- 1
- Primary Topic
- Computational Drug Discovery Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.50