Femoral Vessel Occlusion Enhances Cardiac and Cerebral Perfusion in a Porcine Model of Cardiac Arrest
CPR with FVO significantly increased mean arterial pressure, cardiac perfusion, and cerebral perfusion over CPR alone. These findings suggest FVO may represent a novel adjunctive strategy and therapeutic opportunity to enhance cerebral and cardiac perfusion, thereby decreasing cardiac arrest morbidity and mortality.
Authors
- Heather Holman (ORCID: https://orcid.org/0000-0002-7830-0797)
- Joshua Y. Kim
- Kristi L. Helke (ORCID: https://orcid.org/0000-0001-9746-0764)
- Jeffrey A. Jones (ORCID: https://orcid.org/0000-0002-5133-0427)
- Rupak Mukherjee (ORCID: https://orcid.org/0000-0003-4093-2200)
- Maren Downing (ORCID: https://orcid.org/0000-0001-5121-4584)
- Kristen M. Quinn (ORCID: https://orcid.org/0000-0002-2373-2074)
- Jennie H. Kwon (ORCID: https://orcid.org/0000-0001-5249-6501)
- Samuel W. Seigler (ORCID: https://orcid.org/0000-0001-5278-2006)
- Benjamin Usry (ORCID: https://orcid.org/0009-0006-8651-5129)
Institutions
- Campbell University (US)
- Medical University of South Carolina (US)
- Veterans Health Administration (US)
- Ralph H. Johnson VA Medical Center (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1161/jaha.124.037413
- Primary Topic
- Cardiac Arrest and Resuscitation
- Type
- article
- Field-Weighted Citation Impact
- 0.00