Comparative Benefits of Primary Percutaneous Coronary Intervention Versus Onsite Fibrinolytic for Patients With ST‐Segment–Elevation Myocardial Infarction: A Quasi‐Experimental Study
Primary PCI offers a mortality benefit compared with O-FT in patients with timely treated ST-segment-elevation myocardial infarction, but treatment delays can mitigate this benefit. In settings with prolonged treatment delays, immediate fibrinolysis may be a more effective strategy. Treatment decisions should incorporate both patient characteristics and health care system constraints to optimize ST-segment-elevation myocardial infarction outcomes.
Authors
- Kenneth A. LaBresh (ORCID: https://orcid.org/0000-0001-9040-1956)
- Shuduo Zhou (ORCID: https://orcid.org/0000-0002-5463-3116)
- Sidney C. Smith (ORCID: https://orcid.org/0000-0003-0480-0454)
- Michael G. Trisolini (ORCID: https://orcid.org/0000-0001-6737-9041)
- Binquan You (ORCID: https://orcid.org/0000-0001-7133-1577)
- Yong Huo (ORCID: https://orcid.org/0000-0002-5407-8773)
- Yinzi Jin (ORCID: https://orcid.org/0000-0003-0634-3955)
- Zhi‐Jie Zheng (ORCID: https://orcid.org/0000-0002-0233-5010)
- Dingcheng Xiang (ORCID: https://orcid.org/0000-0001-5628-6878)
- Weiyi Fang
- Feng Liu (ORCID: https://orcid.org/0000-0002-7441-341X)
- Siwei Xie (ORCID: https://orcid.org/0009-0000-1602-2296)
Institutions
- King University (US)
- University of North Carolina at Chapel Hill (US)
- Northeastern University (US)
- Johns Hopkins University (US)
- RTI International (US)
- Peking University (CN)
- Fudan University (CN)
- Kowloon Hospital (CN)
- Suzhou Kowloon Hospital (CN)
- Huadong Hospital (CN)
- General Hospital of Guangzhou Military Command (CN)
- Southern Command Hospital (IN)
- Peking University First Hospital (CN)
- Universidad del Noreste (MX)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1161/jaha.125.041995
- Primary Topic
- Acute Myocardial Infarction Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00