Aging and IGF-I: relationships with vitamin D and body composition. A mediation analysis
These findings provide further evidence of a positive correlation between IGF-I and lean body mass and suggest that IGF-I may mediate the physiological effect of Vitamin D on FFM, highlighting their potential roles in assessing pre-frailty and personalizing nutrition interventions.
Authors
- Pasquale Pignatelli (ORCID: https://orcid.org/0000-0002-2265-7455)
- Roberto Vicinanza
- Alessio Molfino (ORCID: https://orcid.org/0000-0002-6432-0236)
- Maria Del Ben (ORCID: https://orcid.org/0000-0003-1199-8454)
- Evaristo Ettorre
- Valentina Mazza
- Giovanni Imbimbo (ORCID: https://orcid.org/0000-0001-8149-9154)
- Jennie Pollard
- Alessandro Frizza
- Miriam N. Martino
Institutions
- University of Southern California (US)
- University of Salerno (IT)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3389/fnut.2025.1585696
- Citations
- 1
- Primary Topic
- Nutrition and Health in Aging
- Type
- article
- Field-Weighted Citation Impact
- 1.16