Evaluating the safety and feasibility of remote ischemic conditioning for slowing cognitive decline in mild Alzheimer’s dementia
This trial aims to determine the safety, feasibility, and potential effectiveness of RIC as a multi-target intervention for mild Alzheimer's dementia by integrating cognitive and neuropsychological assessments with biological markers, providing a foundation for future studies.
Authors
- Omar Elmadhoun
- Yuchuan Ding (ORCID: https://orcid.org/0000-0001-5358-1660)
- Xiaokun Geng (ORCID: https://orcid.org/0000-0001-8918-8748)
- Qiling Ji (ORCID: https://orcid.org/0000-0003-4728-4541)
- Teng Tong (ORCID: https://orcid.org/0000-0003-0261-7322)
- Yanfang Zeng (ORCID: https://orcid.org/0009-0009-4304-3514)
- Xin Huang (ORCID: https://orcid.org/0000-0001-8050-5452)
- Lipeng Cai
Institutions
- Wayne State University (US)
- Beijing Luhe Hospital Affiliated to Capital Medical University (CN)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Frontiers in Neurology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3389/fneur.2025.1592829
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00