Network pharmacology integrated with molecular docking and experimental validation elucidates the therapeutic potential of Forsythiae Fructus extract against hepatitis B virus-related hepatocellular carcinoma
The therapeutic potential of FF in HBV-related HCC was demonstrated, with its mechanism likely involving the regulation of multiple components, targets, and pathways. These findings establish a solid scientific foundation for exploring FF as a therapeutic option for HBV-related HCC.
Authors
- Changzhou Chen (ORCID: https://orcid.org/0000-0003-2746-9071)
- Jianyin Zhou (ORCID: https://orcid.org/0000-0002-4396-4518)
- Yifan Cai (ORCID: https://orcid.org/0000-0002-3681-2890)
- Fuqing Chen
Institutions
- Xiamen University (CN)
- Zhongshan Hospital of Xiamen University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-06-24
- DOI
- https://doi.org/10.3389/fonc.2025.1571537
- Primary Topic
- Phytochemistry and Biological Activities
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Fujian Province