Optimized laser speckle–based imaging system and methods for deep tissue cerebral blood flow imaging in small rodents
We have validated our system through functional studies, demonstrating its capability to detect enhanced blood flow changes across the olfactory bulbs and somatosensory cortex in rodents with potential for broad applications in preclinical research.
Authors
- Murali Krishnamoorthy
- Nixon M. Abraham (ORCID: https://orcid.org/0000-0001-8523-716X)
- Ria Paul (ORCID: https://orcid.org/0000-0002-8646-9306)
- Shruti D. Marathe
- Soumyajit Sarkar (ORCID: https://orcid.org/0000-0003-4921-9284)
- Hari M. Varma (ORCID: https://orcid.org/0000-0003-0664-1207)
- Susweta Das
Institutions
- Indian Institute of Technology Bombay (IN)
- Indian Institute of Science Education and Research Pune (IN)
Publication Details
- Journal
- Neurophotonics
- Published
- 2025-06-24
- DOI
- https://doi.org/10.1117/1.nph.12.2.025017
- Primary Topic
- Thermoregulation and physiological responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Wellcome Trust
- Department of Biotechnology, Ministry of Science and Technology, India
- Indian Institute of Technology Bombay
- The Wellcome Trust DBT India Alliance
- Biotechnology Industry Research Assistance Council