Unusual malposition of peripherally inserted central catheters into the thymic vein and middle thyroid vein: A case series

Although neither patient experienced significant catheter tip-related events, the delayed diagnostic process led to the presentation of these 2 unusual cases, to guide further recognition of this complication. Some principles should be followed to avoid rare PICC malposition and its fatal complications, including verification of tip before using catheter, use of real-time imaging guidance, regular monitoring of long-term dwelling catheter, and proactive assessment of catheter or direct communication with radiologists particularly in cases where catheter tip malposition is highly suspected.